EXHIBIT 15

ACKNOWLEDGMENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

To the Board of Directors and Shareholders

of Mediware Information Systems, Inc.

We are aware of the incorporation by reference in the following Mediware Information Systems, Inc. (the “Company”) Registration Statements (including all amendments thereto) of our review report, dated November 6, 2012, relating to the unaudited consolidated interim financial statements of the Company, included in the Quarterly Report on Form 10-Q for the quarter ended September 30, 2012.

Form S-8 No. 333-178313

Form S-8 No. 333-130576

Form S-8 No. 333-123496

Form S-8 No. 333-119503

Form S-4 No. 333-57693 (Amendment No. 1)

Form S-8 No. 333-07591

Form S-8 No. 333-83016

/s/ EisnerAmper LLP

New York, New York

November 6, 2012