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Property and Equipment, Net (Tables)
 12 Months Ended
Dec. 31, 2022
Property, Plant and Equipment [Abstract]  
Schedule of estimated useful lives for property and equipment We provide for depreciation and amortization primarily using the straight-line method by charges to the consolidated statements of income in amounts that allocate the cost of property and equipment over their estimated useful lives as follows:
Asset Classification Estimated Useful Life
  
Land improvements 
15 to 20 years
Buildings and improvements 
10 to 40 years
Leasehold improvements Shorter of remaining lease term or useful life of improvements
Machinery and equipment 
3 to 8 years
Office furniture and equipment 
3 to 7 years
Computer hardware and software 
3 to 7 years
Schedule of property and equipment
Property and equipment, net, consisted of the following:
(in thousands)December 31, 2022December 31, 2021
  
Land and improvements$22,221 $22,642 
Buildings and improvements356,049 329,091 
Leasehold improvements107,251 93,248 
Machinery and equipment404,963 382,753 
Office furniture and equipment71,625 69,090 
Computer hardware and software295,969 276,895 
Construction in progress97,310 62,339 
1,355,388 1,236,058 
Less accumulated depreciation and amortization705,914 648,391 
Total property and equipment, net$649,474 $587,667 
Summary of depreciation and amortization, capitalized computer software for internal use and unpaid property equipment reflected in accounts payable and accrued expenses
Below are the amounts of depreciation and amortization of property and equipment, capitalized computer software for internal use, unpaid property and equipment reflected in accounts payable and accrued expenses, and rental and reagent rental program instruments transferred from inventory to property and equipment:
For the Years Ended December 31,
(in thousands)202220212020
   
Depreciation and amortization expense$96,746 $92,376 $86,095 
Capitalized computer software developed for internal use$20,329 $14,753 $18,472 
Unpaid property and equipment, reflected in accounts payable and accrued liabilities$18,334 $19,326 $13,343 
Rental and operating-type reagent rental program instruments transferred from inventory to property and equipment (Note 3)$17,407 $11,628 $9,645