X0303 4 2008-07-29 0 0000874663 ALKERMES INC ALKS 0001126490 POPS RICHARD F 88 SIDNEY STREET CAMBRIDGE MA 02139 1 0 0 0 Common Stock 2008-07-29 4 M 0 25000 5.94 A 440459 D Common Stock 2008-07-29 4 S 0 25000 15.2063 D 415459 D Incentive Stock Option (right to buy) 5.94 2008-07-29 4 M 0 25000 0 D 1999-09-21 2008-09-21 Common Stock 25000 8668 D This option exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. The range of sale prices was $15.09 to $15.43. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon request. The option becomes exercisable in equal annual installments over a four-year period, at the rate of 25% per year commencing one year after the date of grant. Jennifer Baptiste, Attorney-in-Fact for Richard F. Pops 2008-07-31