X0201 4 2004-04-20 0 0000874663 ALKERMES INC ALKS 0001126490 POPS RICHARD F 10555 SCIENCE CENTER DR SAN DIEGO CA 92121 1 1 0 0 Chief Executive Officer Common Stock 2004-04-20 4 M 0 15000 1.845 A 310690 D Common Stock 2004-04-20 4 S 0 15000 15.4322 D 310690 D Common Stock 2004-04-20 4 M 0 6500 1.845 A 304190 D Common Stock 2004-04-20 4 S 0 6500 15.41 D 304190 D Non-Qualified Stock Option (right to buy) 1.845 2004-04-20 4 M 0 15000 15.4322 D 1998-07-21 2004-07-21 Common Stock 15000 50000 D Non-Qualified Stock Option (right to buy) 1.845 2004-04-20 4 M 0 6500 15.41 D 1998-07-21 2004-07-21 Common Stock 6500 43500 D Grant to reporting person of non-qualified stock option pursuant to the Alkermes, Inc. Amended and Restated 1990 Omnibus Stock Option Plan. This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. The option becomes exercisable in equal installments over a four year period, at the rate of 25% per year, commencing one year after the date of grant. Tandem LSAR granted with respect to option. Patricia L. Allen, Attorney-in-Fact 2004-04-22 For: Richard F. Pops 2004-04-22