0000874015 2026-04-21 2026-04-21 false 0000874015 8-K 2026-04-21 IONIS PHARMACEUTICALS, INC. DE 000-19125 33-0336973 2855 Gazelle Court Carlsbad CA 92010 760 931-9200 false false false false Common Stock, $.001 Par Value IONS NASDAQ false