Collaborative Arrangements and Licensing Agreements, Satellite Company Collaborations - OncoGenex Technologies Inc. (Details) - USD ($) $ in Thousands	3 Months Ended								12 Months Ended
	Dec. 31, 2016	Sep. 30, 2016	Jun. 30, 2016	Mar. 31, 2016	Dec. 31, 2015	Sep. 30, 2015	Jun. 30, 2015	Mar. 31, 2015	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Collaborative Arrangement and Licensing Agreement [Abstract]
Revenue earned	$ 160,349	$ 110,927	$ 38,470	$ 36,874	$ 51,571	$ 49,121	$ 120,428	$ 62,583	$ 346,620	$ 283,703	$ 214,161
OncoGenex Technologies Inc. [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Maximum amount of payments receivable for development and regulatory milestones	5,800								5,800
Maximum amount of payments receivable for development milestones	1,300								1,300
Maximum amount of payments receivable for regulatory milestones	4,500								4,500
Next prospective milestone	$ 1,300								1,300
Revenue earned									$ 1,400	$ 0	$ 0