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Collaborative Arrangements and Licensing Agreements, Satellite Company Collaborations - Achaogen, Inc. (Details)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Sep. 30, 2014
USD ($)
Dec. 31, 2016
USD ($)
Sep. 30, 2016
USD ($)
Jun. 30, 2016
USD ($)
Mar. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
Sep. 30, 2015
USD ($)
Jun. 30, 2015
USD ($)
Mar. 31, 2015
USD ($)
Dec. 31, 2016
USD ($)
Drug
Dec. 31, 2015
USD ($)
Dec. 31, 2014
USD ($)
Dec. 31, 2006
USD ($)
Collaborative Arrangement and Licensing Agreement [Abstract]                          
Revenue earned   $ 160,349 $ 110,927 $ 38,470 $ 36,874 $ 51,571 $ 49,121 $ 120,428 $ 62,583 $ 346,620 $ 283,703 $ 214,161  
Achaogen, Inc. [Member]                          
Collaborative Arrangement and Licensing Agreement [Abstract]                          
Upfront fee in the form of equity securities                         $ 1,500
Number of drugs to be developed and commercialized | Drug                   2      
Maximum amount of payments receivable for development, regulatory and commercialization milestones   49,300               $ 49,300      
Cumulative payments received   7,000               7,000      
Milestone payment earned $ 4,000                        
Next prospective milestone   $ 7,500               7,500      
Revenue earned                   $ 0 $ 0 4,000  
Net proceeds from sale of stock                       $ 1,300