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- References

No definition available.

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The license fee payment receivable per drug under the collaboration agreement.

No definition available.

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The maximum amount of payments receivable for milestones under the collaboration agreement.

No definition available.

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Data Type:	xbrli:monetaryItemType
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The percentage of license fees, milestone payments and royalties paid as sublicense fee under the collaboration agreement.

No definition available.

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The amount of the upfront payment received during the period under the collaboration agreement that was paid as a sublicense fee.

No definition available.

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The amount of the upfront payment received during the period under the collaboration agreement that was retained by the entity.

No definition available.

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Royalty percentage received on the sales of a drug by a collaboration partner under the collaboration agreement.

No definition available.

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The amount of upfront payments received during the period under the collaboration agreement.

No definition available.

Name:	ions_UpfrontPaymentReceived
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The cash inflow from the additional capital contribution to the entity.

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Glossary Financing Activities
-URI http://asc.fasb.org/extlink&oid=6513228

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 14
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=66902209&loc=d3e3255-108585

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Number of new stock issued during the period.

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
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-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682

Reference 2: http://www.xbrl.org/2003/role/presentationRef
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-URI http://asc.fasb.org/extlink&oid=27012166&loc=d3e187085-122770

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Name:	dei_LegalEntityAxis=ions_AkceaTherapeuticsIncMember
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