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Organization and Significant Accounting Policies, Research, Development and Patent Expenses (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Research, Development and Patent Expenses [Abstract]      
Research and development expenses $ 340.4 $ 319.5 $ 238.9
Patents [Member]      
Patents [Abstract]      
Estimated useful life 10 years 1 month 6 days    
Cost $ 28.8 27.5  
Accumulated amortization 8.4 8.2  
Estimated Amortization Expense [Abstract]      
2017 1.4    
2018 1.3    
2019 1.2    
2020 1.1    
2021 1.0    
Patent expenses 3.9 2.8 2.9
Non-cash charges related to write-down 2.3 1.1 1.3
Collaborative Agreements [Member]      
Research, Development and Patent Expenses [Abstract]      
Research and development expenses $ 187.1 $ 161.7 $ 85.6