0001104659-19-019394.txt : 20190402 0001104659-19-019394.hdr.sgml : 20190402 20190402163334 ACCESSION NUMBER: 0001104659-19-019394 CONFORMED SUBMISSION TYPE: SC 13D/A PUBLIC DOCUMENT COUNT: 1 FILED AS OF DATE: 20190402 DATE AS OF CHANGE: 20190402 SUBJECT COMPANY: COMPANY DATA: COMPANY CONFORMED NAME: AKCEA THERAPEUTICS, INC. CENTRAL INDEX KEY: 0001662524 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 472608175 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13D/A SEC ACT: 1934 Act SEC FILE NUMBER: 005-90051 FILM NUMBER: 19725434 BUSINESS ADDRESS: STREET 1: 22 BOSTON WHARF RD STREET 2: 9TH FLOOR CITY: BOSTON STATE: MA ZIP: 02210 BUSINESS PHONE: 617-207-0202 MAIL ADDRESS: STREET 1: 22 BOSTON WHARF RD STREET 2: 9TH FLOOR CITY: BOSTON STATE: MA ZIP: 02210 FILED BY: COMPANY DATA: COMPANY CONFORMED NAME: IONIS PHARMACEUTICALS INC CENTRAL INDEX KEY: 0000874015 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 330336973 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13D/A BUSINESS ADDRESS: STREET 1: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 BUSINESS PHONE: 7609319200 MAIL ADDRESS: STREET 1: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 FORMER COMPANY: FORMER CONFORMED NAME: ISIS PHARMACEUTICALS INC DATE OF NAME CHANGE: 19930328 SC 13D/A 1 a19-7643_1sc13da.htm SC 13D/A

 

 

SECURITIES AND EXCHANGE COMMISSION

 

 

Washington, DC 20549

 

 

 

 

 

SCHEDULE 13D

 

 

Under the Securities Exchange Act of 1934
(Amendment No. 4)*

 

Akcea Therapeutics, Inc.

(Name of Issuer)

 

Common Stock

(Title of Class of Securities)

 

00972L 107

(CUSIP Number)

 

Elizabeth L. Hougen

Ionis Pharmaceuticals, Inc.

2855 Gazelle Court

Carlsbad, CA 92010

(760) 931-9200

(Name, Address and Telephone Number of Person
Authorized to Receive Notices and Communications)

 

March 29, 2019

(Date of Event Which Requires Filing of this Statement)

If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. o

 

Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See Rule 13d-7 for other parties to whom copies are to be sent.

 

* The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.

 

The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

 

 

CUSIP No. 00972L 107

13D

 

 

 

1.

Name of Reporting Persons
Ionis Pharmaceuticals, Inc. (“Ionis”)

 

 

2.

Check the Appropriate Box if a Member of a Group (See Instructions)

 

 

(a)

 o

 

 

(b)

 o

 

 

3.

SEC Use Only

 

 

4.

Source of Funds (See Instructions)
WC

 

 

5.

Check if Disclosure of Legal Proceedings Is Required Pursuant to Items 2(d) or 2(e)     o

 

 

6.

Citizenship or Place of Organization
Delaware

 

Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With

7.

Sole Voting Power
70,221,338

 

8.

Shared Voting Power

 

9.

Sole Dispositive Power
70,221,338

 

10.

Shared Dispositive Power

 

 

11.

Aggregate Amount Beneficially Owned by Each Reporting Person
70,221,338

 

 

12.

Check if the Aggregate Amount in Row (11) Excludes Certain Shares (See Instructions)   o

 

 

13.

Percent of Class Represented by Amount in Row 11
75.8%

 

 

14.

Type of Reporting Person (See Instructions)
CO

 

2

 

Item 1.                                 Security and Issuer.

 

This Amendment No. 4 to Schedule 13D is being filed as an amendment to the initial statement on Schedule 13D relating to the Common Stock, $0.001 par value per share (“Common Stock”) of Akcea Therapeutics, Inc., a Delaware corporation (the “Issuer”) as filed with the Securities and Exchange Commission (the “SEC”) on July 27, 2017 (the “Original Schedule 13D”) as amended by Amendment No. 1 filed April 26, 2018,  Amendment No. 2 filed August 7, 2018 and Amendment No. 3 filed October 22, 2018.  The principal executive offices of the Issuer are located at 22 Boston Wharf Road, 9th Floor, Boston, Massachusetts 02210.  This Amendment is being filed to report the acquisition of an aggregate of 2,837,373 shares of the Issuer’s Common Stock by Ionis Pharmaceuticals, Inc., a Delaware corporation (“Ionis” or the “Reporting Person”), on March 29, 2019.

 

Items 2(c), 4 and 5 of the Original Schedule 13D are hereby amended and supplemented to the extent hereinafter expressly set forth and, except as amended and supplemented hereby, the Original Schedule 13D remains in full force and effect.  All capitalized terms used in this Amendment No. 4 but not defined herein shall have the meanings ascribed thereto in the Original Schedule 13D.

 

Item 2.                                 Identity and Background.

 

Schedule A to Item 2(c) is hereby amended.

 

Item 4.                                 Purpose of Transaction.

 

Item 4 of the Original Schedule 13D is hereby amended and supplemented by adding the following paragraph at the end of Item 4:

 

On March 29, 2019, the Reporting Person received 2,837,373 shares of the Issuer’s Common Stock in satisfaction of the Issuer’s obligations to the Reporting Person pursuant to that certain Development, Commercialization and License Agreement, dated December 18, 2015, between the Issuer and the Reporting Person.

 

Item 5.                                 Interest in Securities of the Issuer.

 

Item 5 of the Original Schedule 13D is hereby amended and restated in its entirety as follows:

 

The following information with respect to the ownership of the Common Stock of the Issuer by the Reporting Person filing this Schedule 13D is provided as of March 29, 2019:

 

(a)         The Reporting Person beneficially owns 70,221,338 shares of the Common Stock of the Issuer, or approximately 75.8% of the Issuer’s outstanding Common Stock.

 

(b)         Ionis has sole power to vote and dispose of the securities of the Issuer held by it.

 

(c)          The Reporting Person has not effected any other transactions in the Issuer’s Common Stock within the past sixty days, except as provided herein.

 

(d)         Not applicable.

 

(e)          Not applicable.

 

Item 6.                                 Contracts, Arrangements, Understandings or Relationships with Respect to Securities of the Issuer.

 

None.

 

3

 

Item 7.                                 Material to be Filed as Exhibits.

 

None.

 

4

 

SIGNATURE

 

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

 

 

Date: April 2, 2019

IONIS PHARMACEUTICALS, INC.

 

 

 

 

 

By:

/s/ Elizabeth L. Hougen

 

 

Elizabeth L. Hougen

 

 

Sr. Vice President, Finance and

 

 

Chief Financial Officer

 

 

The original statement shall be signed by each person on whose behalf the statement is filed or his authorized representative. If the statement is signed on behalf of a person by his authorized representative (other than an executive officer or general partner of the filing person), evidence of the representative’s authority to sign on behalf of such person shall be filed with the statement:  provided, however, that a power of attorney for this purpose which is already on file with the Commission may be incorporated by reference. The name and any title of each person who signs the statement shall be typed or printed beneath his signature.

 

Attention:                                        Intentional misstatements or omissions of fact
constitute Federal criminal violations (See 18 U.S.C. 1001)

 

5

 

SCHEDULE A
DIRECTORS AND EXECUTIVE OFFICERS OF IONIS

 

The following table sets forth the name, business address, present principal occupation or employment and material occupations, positions, offices or employment of each of the directors and executive officers of Ionis.  All directors and executive officers listed below are citizens of the United States unless otherwise noted herein.

 

DIRECTORS

 

Name

 

Current Principal Affiliation

 

Business Address

Stanley T. Crooke, M.D., Ph.D.

 

Chairman of the Board and Chief Executive Officer, Ionis Pharmaceuticals, Inc.

 

c/o Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010

B. Lynne Parshall, Esq.

 

Senior Strategic Advisor to Ionis Pharmaceuticals, Inc.

 

c/o Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010

Spencer R. Berthelsen, M.D.

 

Chairman and Managing Director, Kelsey-Seybold Clinic

 

c/o Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010

Breaux Castleman

 

President and Chief Executive Officer, Syntiro Healthcare Services, Inc.

 

c/o Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010

Joseph Klein, III

 

Managing Director, Gauss Capital Advisors, LLC

 

c/o Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010

Joseph Loscalzo, M.D., Ph.D.

 

Head of Department of Medicine and Physician-in-Chief, Brigham & Woman’s Hospital, Harvard Medical School

 

c/o Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010

Brett P. Monia, Ph.D.

 

Chief Operating Officer and Senior Vice President, Translational Medicine, Ionis Pharmaceuticals, Inc.

 

c/o Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010

Frederick T. Muto, Esq.

 

Partner, Cooley LLP

 

c/o Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010

Joseph H. Wender

 

Senior Consultant, Goldman Sachs & Co.

 

c/o Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010

Michael Hayden

 

Killam Professor at the University of British Columbia and the Director of the Translational Laboratory in Genetic Medicine

 

c/o Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010

Peter N. Reikes

 

Vice Chairman, Investment Banking Division, Stifel, Nicolaus & Company, Inc.

 

c/o Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010

 

OFFICERS

 

Name

 

Position

 

Business Address

Stanley T. Crooke, M.D., Ph.D.

 

Chief Executive Officer

 

c/o Ionis Pharmaceuticals, Inc.

 

6

 

 

 

 

 

2855 Gazelle Court
Carlsbad, CA 92010

Brett P. Monia, Ph.D.

 

Chief Operating Officer and Senior Vice President, Translational Medicine

 

c/o Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010

Elizabeth Hougen

 

Senior Vice President, Finance and Chief Financial Officer

 

c/o Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010

C Frank Bennett

 

Senior Vice President, Research

 

c/o Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010

Richard S. Geary, Ph.D.

 

Senior Vice President, Development

 

c/o Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010

Patrick R. O’Neil, Esq.

 

Senior Vice President, Legal and General Counsel

 

c/o Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010

Damien McDevitt, Ph.D.

 

Chief Business Officer

 

c/o Ionis Pharmaceuticals, Inc.
2855 Gazelle Court
Carlsbad, CA 92010

 

7