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Significant Accounting Policies (Details 2) (USD $)
In Thousands, unless otherwise specified
9 Months Ended 1 Months Ended
Sep. 30, 2012
Dec. 31, 2011
Sep. 30, 2012
Maximum
Sep. 30, 2012
Regulus Therapeutics Inc.
Minimum
Oct. 31, 2012
Regulus Therapeutics Inc.
Maximum
Cash, cash equivalents and short-term investments          
Ownership percentage after sale     20.00%   20.00%
Equity method investments, ownership percentage       20.00%  
Inventory valuation          
Raw materials $ 6,737 $ 4,139