EX-99.1 2 a06-6054_1ex99d1.htm EXHIBIT 99

Exhibit 99.1

 

 

ISIS PHARMACEUTICALS, INC.

1896 Rutherford Road

Carlsbad, CA 92008

 

MEMORANDUM

 

 

 

 

Date:                                                                   February 27, 2006

 

To:                                                                              STANLEY T. CROOKE

 

From:                                                               Joseph H. Wender

 

Subject:                                                     SEVERANCE BENEFIT AMENDMENT

 

 

 

Dear Stan:

 

By letter dated April 8, 2003 the Company offered you a 36 month lump sum severance payment to be made in the event that your employment was terminated as a result of a Change of Control.  The Company now extends the Severance Period for so long as you are employed by the Company.

 

Yours truly,

 

/s/ Joseph H. Wender

 

Joseph H. Wender

Chairman, Compensation Committee

 

Telephone 760-603-3848

 

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