CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Sep. 30, 2025	Dec. 31, 2024
Current assets:
Cash and cash equivalents	$ 338,341	$ 242,077
Short-term investments	1,901,830	2,055,579
Contracts receivable	24,608	92,188
Inventories	10,470	12,512
Other current assets	243,744	217,934
Total current assets	2,518,993	2,620,290
Property, plant and equipment, net	106,117	94,251
Right-of-use assets	241,993	161,856
Deposits and other assets	165,988	127,278
Total assets	3,033,091	3,003,675
Current liabilities:
Accounts payable	14,326	42,964
Accrued compensation	57,019	69,614
Accrued liabilities	99,310	108,438
Income taxes payable	101	34
0 percent convertible senior notes, net	630,911	0
Current portion of deferred contract revenue	76,986	78,989
Other current liabilities	24,803	9,279
Total current liabilities	903,456	309,318
Long-term deferred contract revenue	107,906	156,504
Liability related to sale of future royalties, net	545,182	542,212
Long-term lease liabilities	262,672	161,805
Long-term obligations	28,785	51,924
Total liabilities	2,415,124	2,415,324
Stockholders’ equity:
Common stock, $0.001 par value; 300,000,000 shares authorized, 161,137,930 and 157,908,815 shares issued and outstanding at September 30, 2025 and December 31, 2024, respectively	161	158
Additional paid-in capital	3,045,585	2,868,812
Accumulated other comprehensive income	(25,978)	(30,811)
Accumulated deficit	(2,401,801)	(2,249,808)
Total stockholders' equity	617,967	588,351
Total liabilities and stockholders’ equity	3,033,091	3,003,675
1.75 Percent Convertible Senior Notes [Member]
Current liabilities:
Convertible senior notes, net	567,123	565,026
0 Percent Convertible Senior Notes [Member]
Current liabilities:
Convertible senior notes, net	$ 0	$ 628,535