Collaborative Arrangements and Licensing Agreements - Ono (Details) - Ono [Member] $ in Thousands	1 Months Ended	3 Months Ended	6 Months Ended
	Mar. 31, 2025 USD ($) PerformanceObligation	Jun. 30, 2025 USD ($)	Jun. 30, 2025 USD ($)	Dec. 31, 2024 USD ($)
Collaborative Arrangements and Licensing Agreements [Abstract]
Maximum amount of payments receivable over term of collaboration		$ 940,000	$ 940,000
Maximum amount of upfront payments over term of collaboration		280,000	280,000
Maximum amount of development milestone payments over term of collaboration		20,000	20,000
Maximum amount of regulatory milestone payments over term of collaboration		20,000	20,000
Maximum amount of sales milestone payments over term of collaboration		620,000	620,000
Cumulative payments received		280,000	280,000
Next payment to be achieved		20,000	20,000
Number of performance obligations identified (in PerformanceObligation) | PerformanceObligation	2
Transaction price	$ 280,000
Revenue		280,000	280,000
Deferred revenue		0	$ 0	$ 0
R&D Services for Sapablursen [Member]
Collaborative Arrangements and Licensing Agreements [Abstract]
Transaction price	278,000
Revenue		278,000
License of Sapablursen [Member]
Collaborative Arrangements and Licensing Agreements [Abstract]
Transaction price	$ 2,000
Revenue		$ 2,000