CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Jun. 30, 2025	Dec. 31, 2024
Current assets:
Cash and cash equivalents	$ 297,304	$ 242,077
Short-term investments	1,992,676	2,055,579
Contracts receivable	52,580	92,188
Inventories	8,481	12,512
Other current assets	226,109	217,934
Total current assets	2,577,150	2,620,290
Property, plant and equipment, net	111,951	94,251
Right-of-use assets	163,933	161,856
Deposits and other assets	132,099	127,278
Total assets	2,985,133	3,003,675
Current liabilities:
Accounts payable	22,800	42,964
Accrued compensation	46,564	69,614
Accrued liabilities	98,957	108,438
Income taxes payable	81	34
0 percent convertible senior notes, net	630,118	0
Current portion of deferred contract revenue	75,910	78,989
Other current liabilities	22,806	9,279
Total current liabilities	897,236	309,318
Long-term deferred contract revenue	125,095	156,504
Liability related to sale of future royalties, net	541,205	542,212
Long-term lease liabilities	164,379	161,805
Long-term obligations	59,074	51,924
Total liabilities	2,353,409	2,415,324
Stockholders’ equity:
Common stock, $0.001 par value; 300,000,000 shares authorized, 159,196,782 and 157,908,815 shares issued and outstanding at June 30, 2025 and December 31, 2024, respectively	159	158
Additional paid-in capital	2,932,747	2,868,812
Accumulated other comprehensive income	(27,987)	(30,811)
Accumulated deficit	(2,273,195)	(2,249,808)
Total stockholders' equity	631,724	588,351
Total liabilities and stockholders’ equity	2,985,133	3,003,675
1.75 Percent Convertible Senior Notes [Member]
Current liabilities:
Convertible senior notes, net	566,420	565,026
0 Percent Convertible Senior Notes [Member]
Current liabilities:
Convertible senior notes, net	$ 0	$ 628,535