CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Mar. 31, 2025	Dec. 31, 2024
Current assets:
Cash and cash equivalents	$ 264,192	$ 242,077
Short-term investments	1,880,960	2,055,579
Contracts receivable	39,707	92,188
Inventories	11,502	12,512
Other current assets	222,571	217,934
Total current assets	2,418,932	2,620,290
Property, plant and equipment, net	102,925	94,251
Right-of-use assets	159,269	161,856
Deposits and other assets	131,822	127,278
Total assets	2,812,948	3,003,675
Current liabilities:
Accounts payable	17,456	42,964
Accrued compensation	26,575	69,614
Accrued liabilities	102,735	108,438
Income taxes payable	126	34
Current portion of deferred contract revenue	81,097	78,989
Other current liabilities	22,304	9,279
Total current liabilities	250,293	309,318
Long-term deferred contract revenue	140,678	156,504
Liability related to sale of future royalties, net	536,141	542,212
Long-term lease liabilities	159,392	161,805
Long-term obligations	55,671	51,924
Total liabilities	2,337,222	2,415,324
Stockholders' equity:
Common stock, $0.001 par value; 300,000,000 shares authorized, 159,041,259 and 157,908,815 shares issued and outstanding at March 31, 2025 (unaudited) and December 31, 2024, respectively	159	158
Additional paid-in capital	2,901,262	2,868,812
Accumulated other comprehensive loss	(28,949)	(30,811)
Accumulated deficit	(2,396,746)	(2,249,808)
Total stockholders' equity	475,726	588,351
Total liabilities and stockholders' equity	2,812,948	3,003,675
1.75 Percent Convertible Senior Notes [Member]
Current liabilities:
Convertible senior notes, net	565,721	565,026
0 Percent Convertible Senior Notes [Member]
Current liabilities:
Convertible senior notes, net	$ 629,326	$ 628,535