0000874015-25-000108.txt : 20250416 0000874015-25-000108.hdr.sgml : 20250416 20250416174012 ACCESSION NUMBER: 0000874015-25-000108 CONFORMED SUBMISSION TYPE: 144 PUBLIC DOCUMENT COUNT: 1 FILED AS OF DATE: 20250416 DATE AS OF CHANGE: 20250416 SUBJECT COMPANY: COMPANY DATA: COMPANY CONFORMED NAME: IONIS PHARMACEUTICALS INC CENTRAL INDEX KEY: 0000874015 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] ORGANIZATION NAME: 03 Life Sciences EIN: 330336973 STATE OF INCORPORATION: CA FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 144 SEC ACT: 1933 Act SEC FILE NUMBER: 000-19125 FILM NUMBER: 25843725 BUSINESS ADDRESS: STREET 1: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 BUSINESS PHONE: 7609319200 MAIL ADDRESS: STREET 1: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 FORMER COMPANY: FORMER CONFORMED NAME: ISIS PHARMACEUTICALS INC DATE OF NAME CHANGE: 19930328 REPORTING-OWNER: COMPANY DATA: COMPANY CONFORMED NAME: Birchler Brian CENTRAL INDEX KEY: 0001970151 ORGANIZATION NAME: FILING VALUES: FORM TYPE: 144 MAIL ADDRESS: STREET 1: C/O IONIS PHARMACEUTICALS, INC. STREET 2: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 144 1 primary_doc.xml 144 0001970151 XXXXXXXX LIVE 0000874015 IONIS PHARMACEUTICALS INC 000-19125 2855 GAZELLE COURT CARLSBAD CA 92010 7609319200 Birchler Brian Officer Common Stock Morgan Stanley Smith Barney

1585 Broadway New York NY 10036

680 19291.60 157897287 04/16/2025 NASDAQ Common Stock 04/15/2025 RSUs granted under 2011 Equity Incentive Plan Ionis Pharmaceuticals N 680 04/15/2025 Compensation N Morgan Stanley Smith Barney

1585 Broadway New York NY 10036

Common Stock 01/16/2025 5400 176580.00 04/16/2025 Brian Birchler