XML 49 R39.htm IDEA: XBRL DOCUMENT v3.24.3
Collaborative Arrangements and Licensing Agreements, AstraZeneca (Details)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Oct. 31, 2024
USD ($)
Sep. 30, 2024
USD ($)
Agreement
Sep. 30, 2023
USD ($)
Sep. 30, 2024
USD ($)
Agreement
Sep. 30, 2023
USD ($)
Dec. 31, 2023
USD ($)
Collaborative Arrangement and Licensing Agreement [Abstract]            
Revenue   $ 133,814 $ 144,207 $ 478,562 $ 463,142  
AstraZeneca [Member]            
Collaborative Arrangement and Licensing Agreement [Abstract]            
Number of collaboration agreements | Agreement   2   2    
Revenue   $ 19,461 $ 15,959 $ 47,106 $ 99,885  
Deferred contract revenue   $ 1,000   $ 1,000   $ 0
AstraZeneca [Member] | Revenue [Member] | Strategic Partner [Member]            
Collaborative Arrangement and Licensing Agreement [Abstract]            
Concentration percentage   15.00% 11.00% 10.00% 22.00%  
AstraZeneca [Member] | Minimum [Member]            
Collaborative Arrangement and Licensing Agreement [Abstract]            
Cumulative payments received   $ 935,000   $ 935,000    
WAINUA [Member]            
Collaborative Arrangement and Licensing Agreement [Abstract]            
Number of collaboration agreements | Agreement   1   1    
Maximum amount of payments receivable over term of collaboration   $ 3,600,000   $ 3,600,000    
Maximum amount of upfront payments over term of collaboration   200,000   200,000    
Maximum amount of development milestone payments over term of collaboration   485,000   485,000    
Maximum amount of sales milestone payments over term of collaboration   $ 2,900,000   $ 2,900,000    
WAINUA [Member] | Subsequent Event [Member]            
Collaborative Arrangement and Licensing Agreement [Abstract]            
Revenue $ 30,000          
WAINUA [Member] | Maximum [Member] | Subsequent Event [Member]            
Collaborative Arrangement and Licensing Agreement [Abstract]            
Next payment to be achieved 200,000          
WAINUA [Member] | Minimum [Member]            
Collaborative Arrangement and Licensing Agreement [Abstract]            
Royalty percentage received on net sales of medicine       20.00%    
WAINUA [Member] | Minimum [Member] | Subsequent Event [Member]            
Collaborative Arrangement and Licensing Agreement [Abstract]            
Next payment to be achieved $ 115,000          
Cardiovascular, Renal and Metabolic Diseases [Member]            
Collaborative Arrangement and Licensing Agreement [Abstract]            
Number of collaboration agreements | Agreement   1   1