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Insider Trading Arrangements
 3 Months Ended
Sep. 30, 2024
shares
Trading Arrangements, by Individual  
Material Terms of Trading Arrangement

During the quarter ended September 30, 2024, our Section 16 officers and directors adopted or terminated contracts, instructions or written plans for the purchase or sale of our securities as noted in the table below.

*
Contract, instruction or written plan intended to satisfy the affirmative defense conditions of Rule 10b5-1(c) under the Exchange Act.
**
“Non-Rule 10b5-1 trading arrangement” as defined in item 408(c) of Regulation S-K under the Exchange Act.

 
Action
  
Date
  
Trading Arrangement
  
Total Shares
to be Sold
  
Expiration Date
Rule 10b5-1*
  
Non-Rule 10b5-1**
Eric Swayze
EVP, Research
  
Termination
  
August 12, 2024
  
X
      
85,614
  
Upon the execution of all instructions provided in the plan
Brian Birchler
EVP, Corporate and Development Operations
  
Adoption
  
August 12, 2024
  
X
      
71,400
  
The earlier to occur of (i) January 2, 2026, and (ii) upon the execution of all instructions provided in the plan
Brett P. Monia
Chief Executive Officer
  
Adoption
  
August 12, 2024
  
X
      
431,245
  
The earlier to occur of (i) May 7, 2026, and (ii) upon the execution of all instructions provided in the plan
C. Frank Bennett
EVP, Chief Scientific Officer
  
Adoption
  
August 12, 2024
  
X
      
111,149
  
The earlier to occur of (i) January 2, 2026, and (ii) upon the execution of all instructions provided in the plan
Joseph Loscalzo
Board Member
  
Adoption
  
August 12, 2024
  
X
      
62,677
  
The earlier to occur of (i) November 10, 2025, and (ii) upon the execution of all instructions provided in the plan
Eric Swayze
EVP, Research
  
Adoption
  
August 14, 2024
  
X
      
177,770
  
The earlier to occur of (i) December 31, 2027, and (ii) upon the execution of all instructions provided in the plan
Shannon L. Devers
EVP, Chief Human Resources Officer
  
Adoption
  
September 3, 2024
  
X
      
123,508
  
The earlier to occur of (i) January 31, 2026, and (ii) upon the execution of all instructions provided in the plan
Spencer Berthelsen
Director
  
Adoption
  
September 11, 2024
  
X
      
16,000
  
The earlier to occur of (i) June 30, 2025, and (ii) upon the execution of all instructions provided in the plan
Termination [Member] | Eric Swayze [Member]  
Trading Arrangements, by Individual  
Name Eric Swayze
Title EVP, Research
Rule 10b5-1 Arrangement Terminated true
Non-Rule 10b5-1 Arrangement Terminated false
Termination Date August 12, 2024
Expiration Date
Aggregate Available 85,614
Adoption [Member] | Eric Swayze [Member]  
Trading Arrangements, by Individual  
Name Eric Swayze
Title EVP, Research
Rule 10b5-1 Arrangement Adopted true
Non-Rule 10b5-1 Arrangement Adopted false
Adoption Date August 14, 2024
Expiration Date December 31, 2027
Arrangement Duration 1235 days
Aggregate Available 177,770
Adoption [Member] | Brian Birchler [Member]  
Trading Arrangements, by Individual  
Name Brian Birchler
Title EVP, Corporate and Development Operations
Rule 10b5-1 Arrangement Adopted true
Non-Rule 10b5-1 Arrangement Adopted false
Adoption Date August 12, 2024
Expiration Date January 2, 2026
Arrangement Duration 509 days
Aggregate Available 71,400
Adoption [Member] | Brett Monia [Member]  
Trading Arrangements, by Individual  
Name Brett P. Monia
Title Chief Executive Officer
Rule 10b5-1 Arrangement Adopted true
Non-Rule 10b5-1 Arrangement Adopted false
Adoption Date August 12, 2024
Expiration Date May 7, 2026
Arrangement Duration 634 days
Aggregate Available 431,245
Adoption [Member] | C. Frank Bennett [Member]  
Trading Arrangements, by Individual  
Name C. Frank Bennett
Title EVP, Chief Scientific Officer
Rule 10b5-1 Arrangement Adopted true
Non-Rule 10b5-1 Arrangement Adopted false
Adoption Date August 12, 2024
Expiration Date January 2, 2026
Arrangement Duration 509 days
Aggregate Available 111,149
Adoption [Member] | Joseph Loscalzo [Member]  
Trading Arrangements, by Individual  
Name Joseph Loscalzo
Title Board Member
Rule 10b5-1 Arrangement Adopted true
Non-Rule 10b5-1 Arrangement Adopted false
Adoption Date August 12, 2024
Expiration Date November 10, 2025
Arrangement Duration 456 days
Aggregate Available 62,677
Adoption [Member] | Shannon L. Devers [Member]  
Trading Arrangements, by Individual  
Name Shannon L. Devers
Title EVP, Chief Human Resources Officer
Rule 10b5-1 Arrangement Adopted true
Non-Rule 10b5-1 Arrangement Adopted false
Adoption Date September 3, 2024
Expiration Date January 31, 2026
Arrangement Duration 516 days
Aggregate Available 123,508
Adoption [Member] | Spencer Berthelsen [Member]  
Trading Arrangements, by Individual  
Name Spencer Berthelsen
Title Director
Rule 10b5-1 Arrangement Adopted true
Non-Rule 10b5-1 Arrangement Adopted false
Adoption Date September 11, 2024
Expiration Date June 30, 2025
Arrangement Duration 293 days
Aggregate Available 16,000