During the quarter ended June 30, 2024, our Section 16 officers and directors adopted or terminated contracts, instructions or written plans for the purchase or sale of our securities as noted in the table below.

*	Contract, instruction or written plan intended to satisfy the affirmative defense conditions of Rule 10b5-1(c) under the Exchange Act.

**	“Non-Rule 10b5-1 trading arrangement” as defined in item 408(c) of Regulation S-K under the Exchange Act.

Action

Date

Trading Arrangement

Total Shares to Be Sold

Expiration Date

Rule 10b5-1*

Non-Rule 10b5-1**

Brett P. Monia

Chief Executive Officer

Termination

June 26, 2024

X

54,442

Upon the execution of all instructions provided in the plan

Richard S. Geary

EVP, Chief Development Officer

Adoption

April 8, 2024

X

241,732

The earlier to occur of (i) July 7, 2025, and (ii) Upon the execution of all instructions provided in the plan

Trading Arrangements, by Individual

Title

Chief Executive Officer

Non-Rule 10b5-1 Arrangement Terminated

false

Arrangement Duration

Name

Richard S. Geary

Rule 10b5-1 Arrangement Adopted

true

Adoption Date

April 8, 2024

Aggregate Available

241,732