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Income Taxes, Reconciliation of Statutory to Effective Tax Rate (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Reconciliation Between Effective and Statutory Tax Rate [Abstract]      
Pre-tax income (loss) $ (333,965) $ (257,985) $ (29,148)
Statutory rate (70,133) (54,177) (6,121)
State income tax net of federal benefit (22,597) (13,622) 4,278
Foreign (22) (49) 143
Net change in valuation allowance 175,388 104,951 2,885
Loss on debt transactions 0 0 262
Tax credits (67,131) (39,729) (23,198)
Deferred tax true-up 4 (20) (24)
Tax rate change 1,023 (3,091) 12,838
Non-deductible compensation 3,814 3,023 5,085
Other non-deductible items 327 57 84
Foreign-derived intangible income benefit (7,493) 0 0
Stock-based compensation 19,546 14,030 4,720
Other (405) 364 (1,503)
Total income tax expense (benefit) $ 32,321 $ 11,737 $ (551)
Reconciliation Between Effective and Statutory Tax Rate Percentage [Abstract]      
Statutory rate 21.00% 21.00% 21.00%
State income tax net of federal benefit 6.80% 5.30% (14.70%)
Foreign 0.00% 0.00% (0.50%)
Net change in valuation allowance (52.50%) (40.70%) (9.90%)
Loss on debt transactions 0.00% 0.00% (0.90%)
Tax credits 20.10% 15.40% 79.60%
Deferred tax true-up 0.00% 0.00% 0.10%
Tax rate change (0.30%) 1.20% (44.00%)
Non-deductible compensation (1.10%) (1.20%) (17.40%)
Other non-deductible items (0.10%) 0.00% (0.30%)
Foreign-derived intangible income benefit 2.20% 0.00% 0.00%
Stock-based compensation (5.90%) (5.40%) (16.20%)
Other 0.10% (0.10%) 5.10%
Effective rate (9.70%) (4.50%) 1.90%