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Cumulative payments received since inception of the collaboration agreement included in the transaction price for the performance obligation.

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No definition available.

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- Definition

Cumulative amount of payments received under the collaboration agreement as of the end of the reporting period.

+ References

No definition available.

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The maximum amount of development milestone payments to be received over the term of the collaboration.

+ References

No definition available.

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- Definition

The maximum amount of license fees to be received over the term of the collaboration.

+ References

No definition available.

+ Details

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- Definition

The maximum amount of payments the Company is eligible to receive over the term of the collaboration.

+ References

No definition available.

+ Details

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- Definition

The maximum amount of regulatory milestone payments to be received over the term of the collaboration.

+ References

No definition available.

+ Details

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- Definition

The maximum amount of sales milestone payments to be received over the term of the collaboration.

+ References

No definition available.

+ Details

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The next payment to be achieved under the collaboration agreement.

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No definition available.

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The number of material components identified in the collaboration agreement under Accounting Standards Codification (ASC) 808, Collaborative Arrangements.

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No definition available.

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- Definition

Percentage of costs associated with the ongoing global Phase 3 development program paid by a collaboration partner under the collaboration agreement.

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No definition available.

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The number of separate performance obligations under the collaboration agreement.

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No definition available.

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The amount of consideration the Company earned or is eligible to earn under the collaboration agreement, including any variable consideration.

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No definition available.

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- Definition

Royalty percentage received on sales of a medicine in the United States by a collaboration partner under the collaboration agreement.

+ References

No definition available.

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The amount of upfront payments received during the period under the collaboration agreement.

+ References

No definition available.

+ Details

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- Definition

For an entity that discloses a concentration risk in relation to quantitative amount, which serves as the "benchmark" (or denominator) in the equation, this concept represents the concentration percentage derived from the division.

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- Definition

Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable.

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Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

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Collaborative Arrangements and Licensing Agreements, AstraZeneca (Details) $ in Thousands	12 Months Ended
	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)	Dec. 31, 2021 USD ($) Component PerformanceObligation	Dec. 31, 2015 USD ($)	Jul. 31, 2015 USD ($) PerformanceObligation
Collaborative Arrangement and Licensing Agreement [Abstract]
Revenue	$ 787,647	$ 587,367	$ 810,456
AstraZeneca [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Revenue	202,236	79,160	$ 254,591
Deferred revenue	$ 0	$ 0
AstraZeneca [Member] \| Revenue [Member] \| Strategic Partner [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Concentration percentage	26.00%	13.00%	31.00%
WAINUA (Eplontersen) [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Maximum amount of payments receivable over term of collaboration	$ 3,600,000
Upfront payment received			$ 200,000
Maximum amount of license fees over term of collaboration	20,000
Maximum amount of development milestone payments over term of collaboration	485,000
Maximum amount of sales milestone payments over term of collaboration	$ 2,900,000
Royalty percentage received on sales of medicine in U.S.	20.00%
Number of material components \| Component			4
Number of separate performance obligations \| PerformanceObligation			1
Transaction price			$ 200,000
Percentage of costs associated with ongoing global Phase 3 development program paid by AstraZeneca	55.00%
Next payment to be achieved	$ 30,000
Revenue	20,000		$ 200,000
WAINUA (Eplontersen) [Member] \| Maximum [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Cumulative payments received	360,000
WAINUA (Eplontersen) [Member] \| ATTRv-PN [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Revenue	50,000
Cardiovascular, Renal and Metabolic Diseases [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Maximum amount of payments receivable over term of collaboration	3,400,000
Upfront payment received				$ 65,000
Maximum amount of license fees over term of collaboration	290,000
Maximum amount of development milestone payments over term of collaboration	865,000
Maximum amount of regulatory milestone payments over term of collaboration	2,200,000
Number of separate performance obligations \| PerformanceObligation					1
Transaction price					$ 65,000
Next payment to be achieved	10,000
Cumulative payments included in transaction price for performance obligation	90,000
Revenue	36,000
Cardiovascular, Renal and Metabolic Diseases [Member] \| Minimum [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Cumulative payments received	$ 300,000