CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Dec. 31, 2023	Dec. 31, 2022
Current assets:
Cash and cash equivalents	$ 399,266	$ 276,472
Short-term investments	1,931,935	1,710,397
Contracts receivable	97,778	25,538
Inventories	28,425	22,033
Other current assets	184,449	168,254
Total current assets	2,641,853	2,202,694
Property, plant and equipment, net	71,043	74,294
Right-of-use assets	171,896	181,544
Deposits and other assets	105,280	75,344
Total assets	2,990,072	2,533,876
Current liabilities:
Accounts payable	26,027	17,921
Accrued compensation	67,727	49,178
Accrued liabilities	147,894	140,101
Income taxes payable	2,151	6,249
0.125 percent convertible senior notes, net	44,332	0
Current portion of deferred contract revenue	151,128	90,577
Other current liabilities	8,831	7,535
Total current liabilities	448,090	311,561
Long-term deferred contract revenue	241,184	287,768
Liability related to sale of future royalties, net	513,736	0
Long-term lease liabilities	170,875	178,941
Long-term obligations	41,836	15,973
Total liabilities	2,603,386	1,960,989
Stockholders' equity:
Common stock, $0.001 par value; 300,000,000 shares authorized, 144,340,526 and 142,057,736 shares issued and outstanding at December 31, 2023 and December 31, 2022, respectively	144	142
Additional paid-in capital	2,215,098	2,059,850
Accumulated other comprehensive loss	(32,645)	(57,480)
Accumulated deficit	(1,795,911)	(1,429,625)
Total stockholders' equity	386,686	572,887
Total liabilities and stockholders' equity	2,990,072	2,533,876
1.75 Percent Convertible Senior Notes [Member]
Current liabilities:
Convertible senior notes, net	562,285	0
0 Percent Convertible Senior Notes [Member]
Current liabilities:
Convertible senior notes, net	625,380	622,242
0.125 Percent Convertible Senior Notes [Member]
Current liabilities:
Convertible senior notes, net	$ 0	$ 544,504