Supplemental Financial Data, Accrued Liabilities (Details) - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Accrued Liabilities [Abstract]
Clinical development expenses	$ 85,694	$ 116,460
In-licensing expenses	12,704	7,945
Commercial expenses	4,704	3,498
Other miscellaneous expenses	9,600	12,198
Total accrued liabilities	$ 112,702	$ 140,101