The parent entity's interest in net assets of the subsidiary, expressed as a percentage.

No definition available.

Name:	us-gaap_MinorityInterestOwnershipPercentageByParent
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:percentItemType
Balance Type:	na
Period Type:	instant

Organization and Significant Accounting Policies, Basis of Presentation (Details) - Akcea [Member]	Dec. 31, 2022	Oct. 31, 2020	Jun. 30, 2017
Basis of Presentation [Abstract]
Percentage ownership	100.00%
Maximum [Member]
Basis of Presentation [Abstract]
Percentage ownership		77.00%	100.00%