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Legal Proceedings (Details) - John Makris, et al. v. Ionis Pharmaceuticals, Inc., et al. [Member]
$ in Millions
1 Months Ended 3 Months Ended 6 Months Ended
Aug. 05, 2021
Plaintiff
Jul. 31, 2022
USD ($)
Jun. 30, 2022
USD ($)
Jun. 30, 2022
USD ($)
Legal Procedings [Abstract]        
Number of plaintiffs | Plaintiff 4      
Legal reserve for proposed litigation settlement     $ 12.5 $ 12.5
Subsequent Event [Member]        
Legal Procedings [Abstract]        
Contribution to settlement agreement by insurance carrier   $ 4.5    
Other Expense [Member]        
Legal Procedings [Abstract]        
Litigation settlement expense     $ 12.5 $ 12.5