Long-Term Obligations and Commitments, Operating Leases (Details) $ in Thousands		1 Months Ended	12 Months Ended
		Jan. 31, 2022 USD ($)	Dec. 31, 2021 USD ($) Option	Dec. 31, 2020 USD ($)	Dec. 31, 2019 USD ($)
Operating Leases [Abstract]
Lease payments to be made over initial term of lease			$ 27,487
Right-of-use operating lease assets	[1]		$ 18,000
Operating Lease, Right-of-Use Asset, Statement of Financial Position [Extensible List]			Other Assets, Noncurrent
Operating lease liabilities	[2]		$ 22,058
Weighted average remaining lease term			6 years 7 months 6 days
Weighted average discount rate			6.00%
Current portion of operating lease liabilities			$ 2,600
Operating Lease, Liability, Current, Statement of Financial Position [Extensible List]			Long-term Obligations, Excluding Convertible Debt, Current
Operating Lease, Liability, Noncurrent, Statement of Financial Position [Extensible List]			Long-term Obligations Excluding Convertible Debt, Noncurrent
Operating lease cash payments			$ 3,300	$ 3,800	$ 3,900
Carlsbad Facility [Member]
Operating Leases [Abstract]
Number of options to extend lease | Option			1
Term of lease extension			5 years
Carlsbad Office Spaces [Member]
Operating Leases [Abstract]
Number of options to extend lease | Option			1
Term of lease extension			5 years
Boston Office Space [Member]
Operating Leases [Abstract]
Term of lease extension			5 years
Initial term of operating lease			123 months
Period of free rent under lease			3 months
Tenant improvement allowance			$ 3,800
Subleased Office Space in Boston [Member] | Subsequent Event [Member]
Operating Leases [Abstract]
Term of sublease		83 months
Period of free rent under sublease		7 months
Lease payments to be received under sublease		$ 9,600
Another Office Space in Boston [Member]
Operating Leases [Abstract]
Number of options to extend lease | Option			1
Term of lease extension			5 years
Initial term of operating lease			91 months
Period of free rent under lease			7 months
Lease payments to be made over initial term of lease			$ 6,800

[1] Included in deposits and other assets on our consolidated balance sheet.

[2] Current portion of $2.6 million was included in current portion of long-term obligations on our consolidated balance sheet, with the difference included in long-term obligations.