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Organization and Significant Accounting Policies, Inventory Valuation (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Inventory Valuation [Abstract]    
Inventory write-off
Raw materials 18,646 16,708
Work in process 5,770 2,252
Finished goods 390 3,005
Total inventory 24,806 21,965
Clinical [Member]    
Inventory Valuation [Abstract]    
Raw materials 14,507 9,206
Commercial [Member]    
Inventory Valuation [Abstract]    
Raw materials $ 4,139 $ 7,502