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Akcea Merger (Tables)
12 Months Ended
Dec. 31, 2021
Akcea Merger [Abstract]  
Akcea Merger

The following table summarizes the severance and retention expenses related to the Akcea Merger that we recognized for the periods indicated (in millions):

 
Year Ended
December 31, 2021
   
Year Ended
December 31, 2020
 
R&D expenses
 
$
5.1
   
$
3.9
 
SG&A expenses
   
6.6
     
11.4
 
Total
 
$
11.7
   
$
15.3
 


The following table summarizes the severance and retention reserve amounts related to the Akcea Merger that we included in accrued compensation for the period indicated (in millions):

 
Year Ended
December 31, 2021
 
Beginning balance as of January 1, 2021
 
$
14.7
 
Amount expensed during the year
   
13.5
 
Reserve adjustments during the year
   
(1.8
)
Net amount expensed during the year
   
11.7
 
Amounts paid during the year
   
(26.4
)
Ending balance as of December 31, 2021
 
$