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Cumulative amount of payments received under the collaboration agreement as of the end of the reporting period.

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No definition available.

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The maximum amount of payments receivable for commercialization milestones under the collaboration agreement.

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No definition available.

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The maximum amount of payments receivable for development milestones under the collaboration agreement.

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The maximum amount of payments receivable for development, regulatory and sales milestones under the collaboration agreement.

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No definition available.

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The maximum amount of payments receivable for regulatory milestones under the collaboration agreement.

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No definition available.

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The next potential payment to be earned under the collaboration agreement.

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No definition available.

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The number of separate performance obligations under the collaboration agreement.

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No definition available.

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The amount of consideration the Company earned or is eligible to earn under the collaboration agreement, including any variable consideration.

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No definition available.

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Royalty percentage received on the net sales of a drug by a collaboration partner under the collaboration agreement.

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No definition available.

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The amount of upfront payments received during the period under the collaboration agreement.

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No definition available.

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- Definition

For an entity that discloses a concentration risk in relation to quantitative amount, which serves as the "benchmark" (or denominator) in the equation, this concept represents the concentration percentage derived from the division.

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Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable.

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Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

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Collaborative Arrangements and Licensing Agreements, Pfizer (Details) $ in Thousands	1 Months Ended	3 Months Ended		12 Months Ended
	Oct. 31, 2019 USD ($) PerformanceObligation	Dec. 31, 2020 USD ($)	Dec. 31, 2019 USD ($)	Dec. 31, 2020 USD ($)	Dec. 31, 2019 USD ($)	Dec. 31, 2018 USD ($)
Collaborative Arrangement and Licensing Agreement [Abstract]
Revenue				$ 729,264	$ 1,122,599	$ 599,674
R&D Revenue [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Revenue				364,565	770,149	$ 344,752
Pfizer [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Upfront payment received	$ 250,000
Maximum amount of payments receivable for development, regulatory and sales milestones		$ 1,300,000		1,300,000
Maximum amount of payments receivable for development milestones		205,000		205,000
Maximum amount of payments receivable for regulatory milestones		250,000		250,000
Maximum amount of payments receivable for commercialization milestones		850,000		$ 850,000
Royalty percentage received on net sales of drug				20.00%
Next prospective payment		50,000		$ 50,000
Number of separate performance obligations \| PerformanceObligation	3
Transaction price	$ 250,000
Revenue		75,000
Deferred revenue		0	$ 1,300	$ 0	$ 1,300
Pfizer [Member] \| Revenue [Member] \| Strategic Partner [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Concentration percentage				11.00%	22.00%
Pfizer [Member] \| Minimum [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Cumulative payments received		$ 330,000		$ 330,000
Pfizer [Member] \| Vupanorsen [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Transaction price	245,600
Revenue			$ 245,600
Pfizer [Member] \| R&D Services for Vupanorsen [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Transaction price	2,200
Pfizer [Member] \| Vupanorsen API [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Transaction price	$ 2,200
Pfizer [Member] \| R&D Revenue [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Revenue				$ 82,100	$ 248,700