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Significant Accounting Policies, Noncontrolling Interest in Akcea (Details) - Akcea [Member] - shares
shares in Millions
3 Months Ended
Dec. 31, 2019
Mar. 31, 2019
Sep. 30, 2019
Dec. 31, 2018
Apr. 30, 2018
Jul. 31, 2017
Jun. 30, 2017
Noncontrolling Interest in Akcea Therapeutics, Inc. [Abstract]              
Percentage ownership   76.00% 75.00% 75.00% 68.00% 68.00% 100.00%
Additional shares of Akcea stock received (in shares)   2.8          
Forecast [Member]              
Noncontrolling Interest in Akcea Therapeutics, Inc. [Abstract]              
Additional shares of Akcea stock received (in shares) 6.9