CONDENSED CONSOLIDATED BALANCE SHEETS (Unaudited) - USD ($) $ in Thousands	Sep. 30, 2019	Dec. 31, 2018
Current assets:
Cash and cash equivalents	$ 247,939	$ 278,820
Short-term investments	1,972,891	1,805,252
Contracts receivable	49,077	12,759
Inventories	19,375	8,582
Other current assets	118,809	102,473
Total current assets	2,408,091	2,207,886
Property, plant and equipment, net	148,717	132,160
Patents, net	26,985	24,032
Long-term deferred tax assets	284,997	290,796
Deposits and other assets	26,199	12,910
Total assets	2,894,989	2,667,784
Current liabilities:
Accounts payable	13,146	28,660
Accrued compensation	24,404	29,268
Accrued liabilities	52,615	47,503
Income taxes payable	1,945	858
Current portion of long-term obligations	2,060	13,749
Current portion of deferred contract revenue	137,607	160,256
Total current liabilities	231,777	280,294
Long-term deferred contract revenue	492,979	567,359
1 percent convertible senior notes	596,355	568,215
Long-term obligations, less current portion	16,016	4,914
Long-term mortgage debt	59,896	59,842
Total liabilities	1,397,023	1,480,624
Stockholders' equity:
Common stock, $0.001 par value; 300,000,000 shares authorized, 140,636,397 and 137,928,828 shares issued and outstanding at September 30, 2019 (unaudited) and December 31, 2018, respectively	141	138
Additional paid-in capital	2,219,090	2,047,250
Accumulated other comprehensive loss	(25,375)	(32,016)
Accumulated deficit	(857,563)	(967,293)
Total Ionis stockholders' equity	1,336,293	1,048,079
Noncontrolling interest in Akcea Therapeutics, Inc.	161,673	139,081
Total stockholders' equity	1,497,966	1,187,160
Total liabilities and stockholders' equity	$ 2,894,989	$ 2,667,784