Organization and Significant Accounting Policies, Research, Development and Patent Expenses (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Research, Development and Patent Expenses [Abstract]
Research and development expenses	$ 411.9	$ 372.5	$ 340.4
Patents [Member]
Patents [Abstract]
Estimated useful life	10 years 1 month 6 days
Cost	$ 32.7	30.8
Accumulated amortization	8.7	8.8
Estimated Amortization Expense [Abstract]
2019	1.7
2020	1.6
2021	1.5
2022	1.4
2023	1.3
Patent expenses	2.6	2.1	3.9
Non-cash charges related to write-down	0.8	0.4	2.3
Collaborative Agreements [Member]
Research, Development and Patent Expenses [Abstract]
Research and development expenses	$ 58.7	$ 59.5	$ 187.1