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Organization and Significant Accounting Policies, Basis of Presentation (Details) - USD ($)
shares in Millions, $ in Millions
3 Months Ended 6 Months Ended 12 Months Ended
Mar. 31, 2017
Jun. 30, 2017
Dec. 31, 2016
Mar. 01, 2019
Dec. 31, 2018
Mar. 31, 2018
Jul. 31, 2017
Subsequent Event [Member]              
Basis of Presentation [Abstract]              
Sublicense fee to be paid in stock by Akcea for license of AKCEA-AP)(a)-L       $ 75      
Additional shares of Akcea stock to be received for license of AKCEA-APO(a)-L (in shares)       2.8      
Akcea [Member]              
Basis of Presentation [Abstract]              
Percentage ownership before IPO 100.00% 100.00% 100.00%        
Percentage ownership         75.00% 68.00% 68.00%