No definition available.

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- Definition

Cumulative amount of payments received under the collaboration agreement as of the end of the reporting period.

+ References

No definition available.

+ Details

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- Definition

The maximum amount of payments receivable for commercialization milestones under the collaboration agreement.

+ References

No definition available.

+ Details

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- Definition

The maximum amount of payments receivable for development milestones under the collaboration agreement.

+ References

No definition available.

+ Details

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- Definition

The maximum amount of payments receivable for license fees and substantive milestones under the collaboration agreement.

+ References

No definition available.

+ Details

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- Definition

The maximum amount of payments receivable for regulatory milestones under the collaboration agreement.

+ References

No definition available.

+ Details

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- Definition

The next potential milestone payment to be earned under the collaboration agreement.

+ References

No definition available.

+ Details

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Data Type:	xbrli:monetaryItemType
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- Definition

The number of drugs currently being advanced under the collaboration agreement.

+ References

No definition available.

+ Details

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- Definition

The amount of upfront payments received during the period under the collaboration agreement.

+ References

No definition available.

+ Details

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- Definition

For an entity that discloses a concentration risk in relation to quantitative amount, which serves as the "benchmark" (or denominator) in the equation, this concept represents the concentration percentage derived from the division.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 275
-SubTopic 10
-Section 50
-Paragraph 18
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- Definition

Amount of deferred revenue as of balance sheet date. Deferred revenue represents collections of cash or other assets related to a revenue producing activity for which revenue has not yet been recognized. Generally, an entity records deferred revenue when it receives consideration from a customer before achieving certain criteria that must be met for revenue to be recognized in conformity with GAAP.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
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-Name Accounting Standards Codification
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- Definition

Amount of revenue recognized from goods sold, services rendered, insurance premiums, or other activities that constitute an earning process. Includes, but is not limited to, investment and interest income before deduction of interest expense when recognized as a component of revenue, and sales and trading gain (loss).

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
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-Name Accounting Standards Codification
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Collaborative Arrangements and Licensing Agreements, GSK (Details) $ in Thousands	1 Months Ended	3 Months Ended								12 Months Ended
	Mar. 31, 2010 USD ($)	Dec. 31, 2017 USD ($) Drug	Sep. 30, 2017 USD ($)	Jun. 30, 2017 USD ($)	Mar. 31, 2017 USD ($)	Dec. 31, 2016 USD ($)	Sep. 30, 2016 USD ($)	Jun. 30, 2016 USD ($)	Mar. 31, 2016 USD ($)	Dec. 31, 2017 USD ($) Drug	Dec. 31, 2016 USD ($)	Dec. 31, 2015 USD ($)
Collaborative Arrangement and Licensing Agreement [Abstract]
Revenue earned		$ 172,299	$ 120,911	$ 104,152	$ 110,304	$ 160,349	$ 110,927	$ 38,470	$ 36,874	$ 507,666	$ 346,620	$ 283,703
GSK [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Number of drugs currently being advanced \| Drug		2								2
Cumulative payments received		$ 162,000								$ 162,000
Upfront payment received	$ 38,000
Maximum amount of payments receivable for license fees and substantive milestones		262,000								262,000
Maximum amount of payments receivable for development milestones		47,500								47,500
Maximum amount of payments receivable for regulatory milestones		120,000								120,000
Maximum amount of payments receivable for commercialization milestones		70,000								70,000
Next prospective milestone		$ 15,000								15,000
Revenue earned										$ 8,600	12,300	$ 33,300
Deferred revenue						$ 2,100					$ 2,100
GSK [Member] \| Revenue [Member] \| Strategic Partner [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Concentration percentage										2.00%	4.00%	12.00%