CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (Unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2017	Mar. 31, 2016
Commercial Revenue:
SPINRAZA royalties	$ 5,211	$ 0
Licensing and other royalty revenue	3,547	1,660
Total commercial revenue	8,758	1,660
Research and development revenue under collaborative agreements	101,546	35,214
Total revenue	110,304	36,874
Expenses:
Research, development and patent	82,638	80,964
Selling, general and administrative	13,677	10,562
Total operating expenses	96,315	91,526
Income (loss) from operations	13,989	(54,652)
Other income (expense):
Investment income	2,280	1,457
Interest expense	(11,363)	(9,490)
Other expense	(1,438)	0
Income (loss) before income tax expense	3,468	(62,685)
Income tax expense	0	(232)
Net income (loss)	$ 3,468	$ (62,917)
Basic net income (loss) per share (in dollars per share)	$ 0.03	$ (0.52)
Shares used in computing basic net income (loss) per share (in shares)	122,861	120,598
Diluted net income (loss) per share (in dollars per share)	$ 0.03	$ (0.52)
Shares used in computing diluted net income (loss) per share (in shares)	124,972	120,598