Organization and Significant Accounting Policies, Research, Development and Patent Expenses (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013
Research, Development and Patent Expenses [Abstract]
Research and development expenses	$ 319.5	$ 238.9	$ 173.7
Estimated Amortization Expense [Abstract]
Non-cash charges related to write-down	$ 1.9	1.3	6.4
Patents [Member]
Patents [Abstract]
Estimated useful life	10 years 2 months 12 days
Cost	$ 27.5	25.0
Accumulated amortization	8.2	7.8
Estimated Amortization Expense [Abstract]
2016	1.4
2017	1.3
2018	1.2
2019	1.1
2020	1.0
Patent expenses	2.8	2.9	10.3
Non-cash charges related to write-down	1.1	1.3	6.4
Collaborations and Licensing Agreements [Member]
Research, Development and Patent Expenses [Abstract]
Research and development expenses	$ 161.7	$ 85.6	$ 51.0