Collaborative Arrangements and Licensing Agreements, Traditional Pharmaceutical Alliances and Licensing - Bayer HealthCare (Details) (Bayer HealthCare [Member], Agreement Entered into in April 2015 [Member], Subsequent Event [Member], USD $) In Millions, unless otherwise specified	0 Months Ended
	May 05, 2015
Collaborative Arrangement and Licensing Agreement [Abstract]
Near-term payments	$ 155
Upfront fee	100
Next prospective milestone	55.0
Minimum [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Percentage of gross margins of sales received as royalties (in hundredths)	20.00%
License Fees, Milestone Payments and Other Payments [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Maximum amount of payments receivable	375.0
Development Milestones [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Maximum amount of payments receivable	120.0
Commercialization Milestones [Member]
Collaborative Arrangement and Licensing Agreement [Abstract]
Maximum amount of payments receivable	$ 110.0