0000874015-15-000033.txt : 20150218 0000874015-15-000033.hdr.sgml : 20150216 20150217173914 ACCESSION NUMBER: 0000874015-15-000033 CONFORMED SUBMISSION TYPE: 4 PUBLIC DOCUMENT COUNT: 1 CONFORMED PERIOD OF REPORT: 20150212 FILED AS OF DATE: 20150217 DATE AS OF CHANGE: 20150217 ISSUER: COMPANY DATA: COMPANY CONFORMED NAME: ISIS PHARMACEUTICALS INC CENTRAL INDEX KEY: 0000874015 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 330336973 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 BUSINESS ADDRESS: STREET 1: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 BUSINESS PHONE: 7609319200 MAIL ADDRESS: STREET 1: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: WENDER JOSEPH H CENTRAL INDEX KEY: 0001073384 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 000-19125 FILM NUMBER: 15624690 MAIL ADDRESS: STREET 1: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 4 1 edgar.xml PRIMARY DOCUMENT X0306 4 2015-02-12 0000874015 ISIS PHARMACEUTICALS INC ISIS 0001073384 WENDER JOSEPH H C/O ISIS PHARMACEUTICALS, INC. 2855 GAZELLE COURT CARLSBAD CA 92010 1 0 0 0 Common Stock 2015-02-12 2015-02-12 4 M 0 10000 3.95 A 47217 I By Trust Common Stock 2015-02-12 2015-02-12 4 S 0 10000 62.146 D 37217 I By Trust Non-Employee Director Stock Option (right to buy) 3.95 2015-02-12 2015-02-12 4 M 0 10000 0 D 2009-07-01 2015-06-30 Common Stock 10000 0 I By Trust Acquired as a result of exercising a stock option that was scheduled to expire on 6/30/2015. The sale was a result of shares owned. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $61.960 to $62.325, inclusive. The reporting person undertakes to provide to Isis Pharmaceuticals, Inc., any security holder of Isis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) on this Form 4. /s/B. Lynne Parshall (attorney-in-fact) 2015-02-17