0000874015-14-000091.txt : 20141031 0000874015-14-000091.hdr.sgml : 20141031 20141031180509 ACCESSION NUMBER: 0000874015-14-000091 CONFORMED SUBMISSION TYPE: 4 PUBLIC DOCUMENT COUNT: 1 CONFORMED PERIOD OF REPORT: 20141030 FILED AS OF DATE: 20141031 DATE AS OF CHANGE: 20141031 ISSUER: COMPANY DATA: COMPANY CONFORMED NAME: ISIS PHARMACEUTICALS INC CENTRAL INDEX KEY: 0000874015 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 330336973 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 BUSINESS ADDRESS: STREET 1: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 BUSINESS PHONE: 7609319200 MAIL ADDRESS: STREET 1: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: PARSHALL B LYNNE CENTRAL INDEX KEY: 0001073385 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 000-19125 FILM NUMBER: 141187526 MAIL ADDRESS: STREET 1: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 4 1 edgar.xml PRIMARY DOCUMENT X0306 4 2014-10-30 0000874015 ISIS PHARMACEUTICALS INC ISIS 0001073385 PARSHALL B LYNNE C/O ISIS PHARMACEUTICALS, INC. 2855 GAZELLE COURT CARLSBAD CA 92010 1 1 0 0 COO & Secretary Common Stock 2014-10-30 2014-10-30 4 M 0 2510 14.69 A 6816 D Common Stock 2014-10-30 2014-10-30 4 S 0 2510 45.121 D 4306 D Common Stock 2014-10-30 2014-10-30 4 M 0 8561 7.25 A 12867 D Common Stock 2014-10-30 2014-10-30 4 S 0 8561 45.121 D 4306 D Employee Stock Option (right to buy) 14.69 2014-10-30 2014-10-30 4 M 0 2510 0 D 2014-01-02 2020-01-29 Common Stock 2510 59770 D Employee Stock Option (right to buy) 7.25 2014-10-30 2014-10-30 4 M 0 8561 0 D 2013-01-03 2019-01-02 Common Stock 8561 21870 D Acquired as a result of exercising a stock option pursuant to Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to Rule 10b5-1 Trading Plan adopted by the reporting person on 7/29/2014. Grant of 1/30/2013 to reporting person of stock options under the Isis Pharmacueticals, Inc. 1989 Stock Option Plan. 25% of the shares subject to the option vested and became exercisable on 1/2/2014. Thereafter, the remaining shares subject to the option vest and become exercisable in 36 equal monthly installments, at the rate of 15,570 shares per year. Following this transaction, the option was exercisable as to 24,737 on 10/30/14. Grant of 1/3/2012 to reporting person of stock options under the Isis Pharmacueticals, Inc. 1989 Stock Option Plan. 25% of the shares subject to the option vested and became exercisable on 1/3/2013. Thereafter, the remaining shares subject to the option vest and become exercisable in 36 equal monthly installments, at the rate of 15,437 shares per year. Following this transaction, the option was exercisable as to 2,573 on 10/30/2014. /s/B. Lynne Parshall 2014-10-31