0000874015-14-000029.txt : 20140131 0000874015-14-000029.hdr.sgml : 20140131 20140131193413 ACCESSION NUMBER: 0000874015-14-000029 CONFORMED SUBMISSION TYPE: 4 PUBLIC DOCUMENT COUNT: 1 CONFORMED PERIOD OF REPORT: 20140129 FILED AS OF DATE: 20140131 DATE AS OF CHANGE: 20140131 ISSUER: COMPANY DATA: COMPANY CONFORMED NAME: ISIS PHARMACEUTICALS INC CENTRAL INDEX KEY: 0000874015 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 330336973 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 BUSINESS ADDRESS: STREET 1: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 BUSINESS PHONE: 7609319200 MAIL ADDRESS: STREET 1: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: PARSHALL B LYNNE CENTRAL INDEX KEY: 0001073385 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 000-19125 FILM NUMBER: 14566242 MAIL ADDRESS: STREET 1: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 4 1 edgar.xml PRIMARY DOCUMENT X0306 4 2014-01-29 0000874015 ISIS PHARMACEUTICALS INC ISIS 0001073385 PARSHALL B LYNNE C/O ISIS PHARMACEUTICALS, INC. 2855 GAZELLE COURT CARLSBAD CA 92010 1 1 0 0 COO Common Stock 2014-01-29 2014-01-29 4 M 0 3972 11.27 A 7994 D Common Stock 2014-01-29 2014-01-29 4 S 0 3972 48.807 D 4022 D Common Stock 2014-01-29 2014-01-29 4 M 0 31028 10.29 A 35050 D Common Stock 2014-01-29 2014-01-29 4 S 0 31028 48.807 D 4022 D Common Stock 2014-01-29 2014-01-29 4 M 0 5000 7.25 A 5000 I By daughter Common Stock 2014-01-29 2014-01-29 4 S 0 5000 48.807 D 0 I By daughter Common Stock 2014-01-29 2014-01-29 4 M 0 5000 7.25 A 5000 I By daughter Common Stock 2014-01-29 2014-01-29 4 S 0 5000 48.807 D 0 I By daughter Common Stock 2014-01-29 2014-01-29 4 M 0 5000 7.25 A 5000 I By son-in-law Common Stock 2014-01-29 2014-01-29 4 S 0 5000 48.807 D 0 I By son-in-law Common Stock 2014-01-30 2014-01-30 4 M 0 23635 10.29 A 27657 D Common Stock 2014-01-30 2014-01-30 4 S 0 23635 50.364 D 4022 D Common Stock 2014-01-30 2014-01-30 4 M 0 15875 7.25 A 19897 D Common Stock 2014-01-30 2014-01-30 4 S 0 15875 50.364 D 4022 D Employee Stock Option (right to buy) 11.27 2014-01-29 2014-01-29 4 M 0 3972 0 D 2014-01-04 2017-01-03 Common Stock 3972 0 D Employee Stock Option (right to buy) 10.29 2014-01-29 2014-01-29 4 M 0 31028 0 D 2015-01-03 2018-01-02 Common Stock 31028 41856 D Employee Stock Option (right to buy) 7.25 2014-01-29 2014-01-29 4 M 0 5000 0 D 2013-01-03 2019-01-02 Common Stock 5000 0 I By daughter Employee Stock Option (right to buy) 7.25 2014-01-29 2014-01-29 4 M 0 5000 0 D 2013-01-03 2019-01-02 Common Stock 5000 0 I By daughter Employee Stock Option (right to buy) 7.25 2014-01-29 2014-01-29 4 M 0 5000 0 D 2013-01-03 2019-01-02 Common Stock 5000 0 I By son-in-law Employee Stock Option (right to buy) 10.29 2014-01-30 2014-01-30 4 M 0 23635 0 D 2015-01-03 2018-01-02 Common Stock 23635 18221 D Employee Stock Option (right to buy) 7.25 2014-01-30 2014-01-30 4 M 0 15875 0 D 2016-01-02 2019-01-02 Common Stock 15875 30874 D Acquired as a result of exercising a stock option pursuant to a Rule 10b5-1 Trading Plan. The purchase and sale reported on this Form 4 was effective pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on 12/30/13. Grant of 1/3/11 to reporting person of stock options under the Isis Pharmaceuticals, Inc. 1989 Stock Option Plan. 25% of the shares subject to the option vested and became exercisable on 1/3/12. Thereafter, the remaining shares subject to the option vest and become exercisable in 36 equal monthly installments, at the rate of 18,221 shares per year. The option shall be fully vested and exercisable on 1/3/15. The option was exercisable as to 54,663 shares on 1/29/14. Grant of 1/3/12 to reporting person of stock options under the Isis Pharmaceuticals, Inc. 1989 Stock Option Plan. 25% of the shares subject to the option vested and became exercisable on 1/3/13. Thereafter, the remaining shares subject to the option vest and become exercisable in 36 equal monthly installments, at the rate of 15,437 shares per year. The option shall be fully vested and exercisable on 1/3/16. The option was exercisable as to 15,875 shares on 1/30/14. /s/B. Lynne Parshall 2014-01-30