0000874015-13-000006.txt : 20130103 0000874015-13-000006.hdr.sgml : 20130103 20130103205208 ACCESSION NUMBER: 0000874015-13-000006 CONFORMED SUBMISSION TYPE: 4 PUBLIC DOCUMENT COUNT: 1 CONFORMED PERIOD OF REPORT: 20130101 FILED AS OF DATE: 20130103 DATE AS OF CHANGE: 20130103 REPORTING-OWNER: OWNER DATA: COMPANY CONFORMED NAME: O'NEIL PATRICK R. CENTRAL INDEX KEY: 0001564926 FILING VALUES: FORM TYPE: 4 SEC ACT: 1934 Act SEC FILE NUMBER: 000-19125 FILM NUMBER: 13509552 MAIL ADDRESS: STREET 1: C/O ISIS PHARMACEUTICALS, INC. STREET 2: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 ISSUER: COMPANY DATA: COMPANY CONFORMED NAME: ISIS PHARMACEUTICALS INC CENTRAL INDEX KEY: 0000874015 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 330336973 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 BUSINESS ADDRESS: STREET 1: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 BUSINESS PHONE: 7609319200 MAIL ADDRESS: STREET 1: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 4 1 edgar.xml PRIMARY DOCUMENT X0306 4 2013-01-01 0000874015 ISIS PHARMACEUTICALS INC ISIS 0001564926 O'NEIL PATRICK R. C/P ISIS PHARMACEUTICALS, INC. 2855 GAZELLE COURT CARLSBAD CA 92010 0 1 0 0 SVP, Legal and General Counsel Common Stock 2013-01-01 2013-01-01 5 J 0 431 8.874 A 2759 D Employee Stock Option (right to buy) 10.82 2013-01-02 2013-01-02 4 A 0 7500 0 A 2020-01-01 Common Stock 7500 7500 D Employee Stock Option (right to buy) 10.82 2013-01-02 2013-01-02 4 A 0 15700 0 A 2020-01-01 Common Stock 15700 15700 D Reporting 431 shares acquired under the Isis Pharmaceuticals, Inc. Amended and Restated 2000 Employee Stock Purchase Plan on January 1, 2013. These 431 shares may not be sold until July 2, 2013. Grant of 1/2/13 to reporting person of stock options under the Isis Pharmaceuticals, Inc. 1989 Stock Option Plan. 25% of the shares subject to the option vest and become exercisable on 1/2/14. Thereafter, the remaining shares subject to the option vest and become exerciable in 36 equal monthly installments, at the rate of 1,875 shares per year. The option is exercisable as to 0 on 1/2/13. Grant of 1/2/13 to reporting person of stock options under the Isis Pharmaceuticals, Inc. 1989 Stock Option Plan. 25% of the shares subject to the option vest and become exercisable on 1/2/14. Thereafter, the remaining shares subject to the option vest and become exerciable in 36 equal monthly installments, at the rate of 3,925 shares per year. The option is exercisable as to 0 on 1/2/13. /s/Patrick R. O'Neil 2013-01-03