0000048532-24-000002.txt : 20240126 0000048532-24-000002.hdr.sgml : 20240126 20240126140941 ACCESSION NUMBER: 0000048532-24-000002 CONFORMED SUBMISSION TYPE: 144 PUBLIC DOCUMENT COUNT: 1 FILED AS OF DATE: 20240126 DATE AS OF CHANGE: 20240126 SUBJECT COMPANY: COMPANY DATA: COMPANY CONFORMED NAME: IONIS PHARMACEUTICALS INC CENTRAL INDEX KEY: 0000874015 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] ORGANIZATION NAME: 03 Life Sciences IRS NUMBER: 330336973 STATE OF INCORPORATION: CA FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 144 SEC ACT: 1933 Act SEC FILE NUMBER: 000-19125 FILM NUMBER: 24566607 BUSINESS ADDRESS: STREET 1: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 BUSINESS PHONE: 7609319200 MAIL ADDRESS: STREET 1: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 FORMER COMPANY: FORMER CONFORMED NAME: ISIS PHARMACEUTICALS INC DATE OF NAME CHANGE: 19930328 REPORTING-OWNER: COMPANY DATA: COMPANY CONFORMED NAME: O'NEIL PATRICK R. CENTRAL INDEX KEY: 0001564926 ORGANIZATION NAME: FILING VALUES: FORM TYPE: 144 MAIL ADDRESS: STREET 1: C/O IONIS PHARMACEUTICALS, INC. STREET 2: 2855 GAZELLE COURT CITY: CARLSBAD STATE: CA ZIP: 92010 144 1 primary_doc.xml 144 0001564926 XXXXXXXX LIVE 0000874015 IONIS PHARMACEUTICALS INC 000-19125 2855 GAZELLE COURT CARLSBAD CA 92010 7609319200 O'NEIL PATRICK R. Officer COMMON STOCK INSIGHT SECURITIES, INC.

600 CENTRAL STE 293 HIGHLAND PARK IL 60035

6450 333787.50 143100000 01/25/2024 NYSE COMMON STOCK 01/16/2023 COMPENSATION IONIS PHARMACEUTICALS, INC. N 6450 01/16/2023 COMPENSATION N PATRICK O'NEIL

2855 GAZELLE COURT CARLSBAD CA 92010

COMMON STOCK 12/26/2023 20825 1072487.50 INSIGHT SECURITIES SOLD 6,450 SHARES OF IONIS PHARMACEUTICALS, INC. FOR PATRICK R. O'NEIL 01/26/2024 11/16/2022 MICHAEL MAKULA