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Summary of Other Non-current Assets (Detail) - USD ($)
$ in Thousands
Mar. 31, 2020
Dec. 31, 2019
Prepaid Expense And Other Assets Noncurrent [Abstract]    
Manufacturing-related deposits and prepaids $ 135,963 $ 122,091
Strategic investments 33,697 31,937
Restricted cash and investments 9,566 9,566
Prepaid clinical expenses 5,164 4,665
Other 2,415 5,600
Total other non-current assets $ 186,805 $ 173,859