Stock Based Compensation - Summary of Stock Awards Granted (Detail) - $ / shares		1 Months Ended	3 Months Ended				9 Months Ended
	Jul. 28, 2026	Sep. 30, 2025	Sep. 30, 2026		Sep. 30, 2025		Sep. 30, 2026		Sep. 30, 2025
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Grants, Stock options			2,224,342	[1]	0		2,224,342	[1]	488,192
Weighted Average Grant Date Fair Value, Stock options			$ 10.48		$ 0		$ 10.48		$ 46.93
Restricted Stock Units [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Grants, Restricted stock units	800,000	3,400,000	967,174	[1]	3,496,155	[2]	1,755,359	[1]	5,191,278	[2]
Weighted Average Grant Date Fair Value, Restricted stock units			$ 16.04		$ 18.95		$ 17		$ 39.73
Performance Shares [Member]
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]
Grants, Restricted stock units			0		225,000	[3]	0		345,378	[4]
Weighted Average Grant Date Fair Value, Restricted stock units			$ 0		$ 18.95		$ 0		$ 47.09

[1] On July 28, 2026 (the "Grant Date"), the Company granted its Chief Executive Officer, Dr. Michael Severino, approximately 2.2 million premium-priced stock options that vest 25% on the first anniversary of the Grant Date, with the remainder vesting monthly over the following three years and approximately 0.8 million restricted stock units (“RSUs”) that vest in equal annual installments over four years, in each case generally subject to continued employment.

[2] In September 2025, approximately 3.4 million RSUs were granted, which will vest over two years while the remaining vest over four years.

[3] In September 2025, RSUs with performance conditions (“PSUs”) were granted (the "September 2025 PSUs"). The performance condition is related to the achievement of a certain financial performance goal. The September 2025 PSUs have a three-year cliff vesting schedule. As of September 30, 2026, the performance condition associated with the September 2025 PSUs has been achieved.

[4] In addition to the September 2025 PSUs, included in PSUs for the nine months ended September 30, 2025 are approximately 0.1 million shares with performance conditions which are related to the achievement of certain financial performance goals, regulatory development and approval of certain of the Company's product candidates and certain manufacturing achievements (the “March 2025 PSUs”). As of September 30, 2026, none of the performance conditions for the March 2025 PSUs were probable of being achieved.