Accrued Expenses - Summary of Accrued Expenses (Detail) - USD ($) $ in Thousands	Sep. 30, 2026	Dec. 31, 2025
Payables and Accruals [Abstract]
Product revenue related reserves	$ 109,098	$ 117,518
Accrued contract manufacturing costs	58,946	92,281
Accrued employee compensation costs	45,812	58,607
Accrued litigation contingency charge	39,000	0
Accrued professional fees	22,015	17,840
Accrued clinical and pre-clinical costs	14,303	18,894
Accrued income taxes	10,217	4,755
Accrued royalties	9,427	10,863
Accrued clinical collaboration costs	3,336	10,222
Accrued interest expense	4,575	20,714
Other	5,035	7,965
Total accrued expenses	$ 321,764	$ 359,659