XML 50 R42.htm IDEA: XBRL DOCUMENT v3.26.3
LICENSE AND COLLABORATION AGREEMENTS - Additional Information (Detail) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Jun. 30, 2025
Sep. 30, 2026
Sep. 30, 2025
Sep. 30, 2026
Sep. 30, 2025
Dec. 31, 2025
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Product revenues, net   $ 323,763 $ 370,043 $ 982,967 $ 1,494,689  
Collaboration and other   57,588 29,313 530,438 260,614  
Loss on strategic investments   $ 523 (36,739) $ 2,683 17,268  
Common stock, shares   198,000,000   198,000,000   198,000,000
ELEVIDYS [Member]            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Product revenues, net   $ 83,450 131,498 $ 283,540 788,334  
Roche Collaboration Agreement [Member]            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Collaboration and other       325,000 112,000  
Arrowhead Pharmaceuticals Inc [Member]            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Research and development expense   5,700 7,000 20,500 15,800  
Collaborative Arrangement | Maximum [Member]            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Development Milestone and Upfront Fee Recognized as Research and Development Expense       12,000,000    
Collaborative Arrangement | Roche Holding A.G. [Member]            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Collaboration and other       365,000 175,500  
Deferred revenue   188,800   188,800   $ 527,300
Deferred Revenue, Current   104,900   104,900   443,400
Research and development expense   7,100 $ 12,200 22,500 $ 66,400  
Collaboration Receivable   41,500   41,500   104,100
Collaborative Arrangement | Roche Collaboration Agreement [Member]            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Collaboration and other       40,000    
Collaborative Arrangement | NationWide Children Hospital [Member]            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Milestone Payment Received $ 63,500          
Collaborative Arrangement | Arrowhead Pharmaceuticals Inc [Member]            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Research and development expense       583,600    
Equity Investment Agreement [Member] | Arrowhead Pharmaceuticals Inc [Member]            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Investment in license agreement   241,400   241,400    
Licensing And Collaboration Agreement [Member] | Arrowhead Pharmaceuticals Inc [Member]            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Up front payment for license and collaboration agreement       500,000    
Investment in license agreement   $ 325,000   $ 325,000    
Term of installment fee       five years    
License agreement fee       $ 250,000    
Annual Installment Fee       $ 50,000    
Upfront Fee To Be Paid On Certain Enrollment Achievement           $ 300,000
Common stock, shares   11,900,000   11,900,000    
Development Milestone and Upfront Fee Recognized as Research and Development Expense       $ 10,300,000    
Licensing And Collaboration Agreement [Member] | Second Arrowhead DM One Milestone [Member]            
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]            
Cash   $ 200,000   $ 200,000