<SEC-DOCUMENT>0001104659-25-070926-index.html : 20250725
<SEC-HEADER>0001104659-25-070926.hdr.sgml : 20250725
<ACCEPTANCE-DATETIME>20250725201443
ACCESSION NUMBER:		0001104659-25-070926
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G/A
PUBLIC DOCUMENT COUNT:		3
FILED AS OF DATE:		20250725
DATE AS OF CHANGE:		20250725

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Sarepta Therapeutics, Inc.
		CENTRAL INDEX KEY:			0000873303
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				930797222
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-54847
		FILM NUMBER:		251152782

	BUSINESS ADDRESS:	
		STREET 1:		215 FIRST STREET
		STREET 2:		SUITE 415
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142
		BUSINESS PHONE:		617-274-4000

	MAIL ADDRESS:	
		STREET 1:		215 FIRST STREET
		STREET 2:		SUITE 415
		CITY:			CAMBRIDGE
		STATE:			MA
		ZIP:			02142

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Sarepta Therapuetics, Inc.
		DATE OF NAME CHANGE:	20120712

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	AVI BIOPHARMA INC
		DATE OF NAME CHANGE:	19980930

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ANTIVIRALS INC
		DATE OF NAME CHANGE:	19970123

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			D. E. SHAW & CO, L.P.
		CENTRAL INDEX KEY:			0001009268
		ORGANIZATION NAME:           	
		EIN:				133695715
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		TWO MANHATTAN WEST
		STREET 2:		375 NINTH AVENUE, 52ND FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10001
		BUSINESS PHONE:		212-478-0000

	MAIL ADDRESS:	
		STREET 1:		TWO MANHATTAN WEST
		STREET 2:		375 NINTH AVENUE, 52ND FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10001

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	SHAW D E & CO L P /NY/
		DATE OF NAME CHANGE:	19990421
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G/A
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
Document 1 - file: primary_doc.html

Document 1 - RAW XML: primary_doc.xml

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24.1
<SEQUENCE>2
<FILENAME>tm2521807d1_ex-1.htm
<DESCRIPTION>EXHIBIT 1
<TEXT>
Document 2 - file: tm2521807d1_ex-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>3
<FILENAME>tm2521807d1_ex-2.htm
<DESCRIPTION>EXHIBIT 2
<TEXT>
Document 3 - file: tm2521807d1_ex-2.htm

</DOCUMENT>
</SEC-DOCUMENT>