Condensed Consolidated Statements of Operations and Comprehensive Income (Loss) (Unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2025	Jun. 30, 2024	Jun. 30, 2025	Jun. 30, 2024
Revenues:
Products, net	$ 513,123	$ 360,548	$ 1,124,646	$ 720,032
Type of Revenue [Extensible List]	us-gaap:ProductMember	us-gaap:ProductMember	us-gaap:ProductMember	us-gaap:ProductMember
Collaboration and other	$ 97,968	$ 2,383	$ 231,301	$ 56,363
Total revenues	611,091	362,931	1,355,947	776,395
Cost and expenses:
Cost of sales (excluding amortization of in-licensed rights)	152,558	44,545	290,122	95,104
Research and development	204,392	179,690	977,840	380,086
Selling, general and administrative	137,897	138,796	271,526	265,799
Amortization of in-licensed rights	667	601	1,268	1,202
Total cost and expenses	495,514	363,632	1,540,756	742,191
Operating income (loss)	115,577	(701)	(184,809)	34,204
Other income (loss), net:
Other income (expense), net	38,061	14,278	(45,071)	20,821
Income (loss) before income tax expense	153,638	13,577	(229,880)	55,025
Income tax (benefit) expense	(43,254)	7,117	20,736	12,446
Segment net income (loss)	196,892	6,460	(250,616)	42,579
Other comprehensive (loss) income:
Unrealized (losses) gains on investments, net of tax	(85)	(339)	167	(1,948)
Total other comprehensive (loss) income	(85)	(339)	167	(1,948)
Comprehensive income (loss)	$ 196,807	$ 6,121	$ (250,449)	$ 40,631
Earnings (loss) per share:
Basic	$ 2.01	$ 0.07	$ (2.57)	$ 0.45
Diluted	$ 1.89	$ 0.07	$ (2.57)	$ 0.44
Weighted average number of shares of common stock used in computing earnings (loss) per share:
Basic	98,005	94,618	97,685	94,305
Diluted	106,623	99,144	97,685	99,129