CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE (LOSS) INCOME - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2025	Mar. 31, 2024
Revenues:
Products, net	$ 611,523	$ 359,484
Type of Revenue [Extensible List]	us-gaap:ProductMember	us-gaap:ProductMember
Collaboration and other	$ 133,333	$ 53,980
Total revenues	744,856	413,464
Cost and expenses:
Cost of sales (excluding amortization of in-licensed rights)	137,564	50,559
Research and development	773,448	200,396
Selling, general and administrative	133,629	127,003
Amortization of in-licensed rights	601	601
Total cost and expenses	1,045,242	378,559
Operating (loss) income	(300,386)	34,905
Other (loss) income, net:
Other (expense) income, net	(83,132)	6,543
(Loss) income before income tax expense	(383,518)	41,448
Income tax expense	63,990	5,329
Net (loss) income	(447,508)	36,119
Other comprehensive income (loss):
Unrealized gains (losses) on investments, net of tax	252	(1,609)
Total other comprehensive income (loss)	252	(1,609)
Comprehensive (loss) income	$ (447,256)	$ 34,510
(Loss) earnings per share:
(Loss) earnings per share, basic	$ (4.6)	$ 0.38
(Loss) earnings per share, diluted	$ (4.6)	$ 0.37
Weighted average number of shares of common stock used in computing (loss) earnings per share:
Basic	97,362,000	93,991,000
Diluted	97,362,000	99,114,000